Publications

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2022
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Highly selective lysine acylation in proteins using a Lys-His tag sequence

Kofoed, Christian ; Wu, Shunliang ; Sørensen, Kasper K. ; Treiberg, Tuule ; Arnsdorf, Johnny ; Bjørn, Sara P. ; Jensen, Tanja L. ; Voldborg, Bjørn G. ; Thygesen, Mikkel B. ; Jensen, Knud J. ; Schoffelen, Sanne
in: Chemistry - A European Journal, vol: 28, issue: 15

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1002/chem.202200147

2021
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Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells

Pérez-Rodriguez, Saumel ; Wulff, Tune ; Voldborg, Bjørn G ; Altamirano, Claudia ; Trujillo-Roldán, Mauricio A ; Valdez-Cruz, Norma A
in: ACS Omega, vol: 6, issue: 19, pages: 12439-12458

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1021/acsomega.0c06030

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In situ detection of protein interactions for recombinant therapeutic enzymes

Samoudi, Mojtaba ; Chung Kuo, Chih ; Robinson, Caressa M. ; Shams-Ud-Doha, Km ; Schinn, Song-Min ; Kol, Stefan ; Weiss, Linus ; Petersen Bjørn, Sara ; Voldborg, Bjørn G. ; Rosa Campos, Alexandre ; Lewis, Nathan E.
in: Biotechnology and Bioengineering, vol: 118, issue: 2, pages: 890-904

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1002/bit.27621

2020
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A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering

Liang, Chenguang ; Chiang, Austin W. T. ; Hansen, Anders H. ; Arnsdorf, Johnny ; Schoffelen, Sanne ; Sorrentino, James T. ; Kellman, Benjamin P. ; Bao, Bokan ; Voldborg, Bjørn G. ; Lewis, Nathan E.
in: Current Research in Biotechnology, vol: 2, pages: 22-36

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.crbiot.2020.01.001

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CHOmics

Lin, Dongdong ; Yalamanchili, Hima B. ; Zhang, Xinmin ; Lewis, Nathan E. ; Alves, Christina S. ; Groot, Joost ; Arnsdorf, Johnny ; Bjørn, Sara P. ; Wulff, Tune ; Voldborg, Bjørn G. ; Zhou, Yizhou ; Zhang, Baohong
in: PLOS Computational Biology, vol: 16, issue: 12

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1371/journal.pcbi.1008498

 

Elucidate Glycosyltransferase Specificities And Interactions for Rational Glycoengineering

Liang, Chenguang ; Chiang, Austin ; Hansen, Anders H. ; Arnsdorf, Johnny ; Schoffelen, Sanne ; Sorrentino, James ; Kellman, Benjamin ; Bao, Bokan ; Voldborg, Bjørn G. ; Lewis, Nathan
in: FASEB Journal, vol: 34, issue: S1

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1096/fasebj.2020.34.s1.06683

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Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis

Pérez-Rodriguez, Saumel ; de Jesús Ramírez-Lira, María ; Wulff, Tune ; Voldbor, Bjørn Gunnar ; Ramírez, Octavio T. ; Trujillo-Roldán, Mauricio A. ; Valdez-Cruz, Norma A.
in: PLOS ONE, vol: 15, issue: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1371/journal.pone.0237930

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Evolution-guided engineering of small-molecule biosensors

Snoek, Tim ; Chaberski, Evan Kirk ; Ambri, Francesca ; Kol, Stefan ; Bjørn, Sara P ; Pang, Bo ; Barajas, Jesus F ; Welner, Ditte Hededam ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Nucleic Acids Research, vol: 48, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1093/nar/gkz954

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Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Gutierrez, Jahir M ; Feizi, Amir ; Li, Shangzhong ; Kallehauge, Thomas B ; Hefzi, Hooman ; Grav, Lise Marie ; Ley, Daniel ; Baycin Hizal, Deniz ; Betenbaugh, Michael J ; Voldborg, Bjørn Gunnar ; Kildegaard, Helene Faustrup ; Min Lee, Gyun ; Palsson, Bernhard O ; Nielsen, Jens ; Lewis, Nathan E
in: Nature Communications, vol: 11, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1038/s41467-019-13867-y